While the Los Angeles Rams will play host to the first-ever Monday night playoff game, it is the Arizona Cardinals who are feeling completely familiar with the lead-up to the all-NFC West wild-card-round matchup.
The Rams-Cardinals primetime showdown will be the third meeting between the teams, with the road team having won the previous two. Los Angeles is a 3.5-point favorite at BetMGM and FanDuel.
While the Rams prevailed in a Monday night meeting at Arizona in December, it was the Cardinals who pronounced themselves playoff-worthy with a Week 4 victory at Los Angeles in early October.
The action has been nearly split at BetMGM with Arizona backed by 52 percent of the bets and 53 percent of the spread-line handle. However, Los Angeles has received the stronger support at FanDuel with 53 and 70 percent, respectively.
Defeats in four of their last five games cost the Cardinals an NFC West title and left them with something to prove Monday. But that was also the case in Week 4, when they arrived in Los Angeles on the heels of three consecutive wins to start the season amid questions of whether their hot start was sustainable.
The Cardinals not only delivered a resounding 37-20 victory over the Rams that day, behind two touchdown passes from Kyler Murray and 120 yards rushing from Chase Edmonds, but they went on to open the season 7-0.
Having gone 4-6 since that undefeated start, the Cardinals are once again having to prove that their time has arrived.
"It's 0-0, and no one remembers the regular season," Cardinals coach Kliff Kingsbury said. "It's what you do here on out, and it's a real opportunity for us to take the next step and see how good we can be."
The game will not only be Murray's playoff debut, but it will be the Cardinals' first appearance in the playoffs since 2015-16, when they defeated the Green Bay Packers in the divisional round but were blown out by the Carolina Panthers in the NFC Championship Game.
Murray averaged 270.5 yards passing per game this season with 24 TDs and 10 interceptions. He had 383 yards passing in Week 14 against the Rams but did not throw a TD pass that day and was intercepted twice in a 30-23 Los Angeles victory.
"I like that we had two games to see how we played them, how they played us and what looked good and didn't," Kingsbury said. "So we can build off that."
The Rams had a hot start of their own, despite their early loss to the Cardinals, opening with a 7-1 record. Then came a midseason slumber when they took consecutive defeats to a trio of playoff teams, the Tennessee Titans, the San Francisco 49ers and the Packers.
The Rams were just 2-5 against playoff teams this season.
Quarterback Matthew Stafford averaged 309.6 yards passing per game with 22 TDs and four interceptions over the first eight games in a Rams uniform, but those stats fell to 267.7 yards passing with 19 TDs and 13 interceptions over the final nine games as Los Angeles went 5-4.
Stafford did help wide receiver Cooper Kupp to a Rams-record 1,947 receiving yards, while Kupp also pulled off the wide receiver triple crown, leading the NFL in receptions (145), TDs (16) and receiving yards.
After their midseason swoon, the Rams pulled together a five-game winning streak that included their victory at Arizona, but questions started anew after their 27-24 defeat in overtime to the 49ers to close out the season. The Rams blew a 17-0, first-half lead.
Los Angeles' offensive and defensive lines were dominated by the 49ers in the season finale, especially in the second half as San Francisco rallied.
"Whether we're playing at home, playing on the road, things are going our way, things aren't going our way, we continue to battle," said Stafford, who has not won a playoff game in three chances. "That's what it takes to win games in the playoffs, there's no question. Right now, it's testing us ... but we're a resilient group and we'll be ready to go."
Rams safety Jordan Fuller is out for the playoffs with an ankle injury and fellow safety Taylor Rapp (concussion) was ruled out Saturday. The injuries led to the Rams signing Eric Weddle out of retirement Wednesday and McVay said he will be activated prior to Monday's game. Linebacker Leonard Floyd (back) will play.
Cardinals defensive end J.J. Watt (shoulder), who hasn't played since Week 7, returned to practice Thursday and was activated Monday. Watt, 32, hasn't played for the Cardinals since Oct. 24. Days later, Watt underwent surgery to repair a torn labrum, bicep, rotator cuff and separated shoulder.
Edmonds (ribs, toe) is slated to play, while fellow running back James Conner (ribs) is listed as questionable. Left guard Justin Pugh (calf) also is questionable.
--Field Level Media